paramlink2: Parametric Linkage Analysis

Parametric linkage analysis of monogenic traits in medical pedigrees. Features include singlepoint analysis, multipoint analysis via 'MERLIN' (Abecasis et al. (2002) <doi:10.1038/ng786>), visualisation of log of the odds (LOD) scores and summaries of linkage peaks. Disease models may be specified to accommodate phenocopies, reduced penetrance and liability classes. 'paramlink2' is part of the 'ped suite' package ecosystem, presented in 'Pedigree Analysis in R' (Vigeland, 2021, ISBN:9780128244302).

Version: 1.0.4
Depends: R (≥ 4.1), pedtools
Imports: pedprobr
Suggests: spelling, testthat
Published: 2023-02-11
DOI: 10.32614/CRAN.package.paramlink2
Author: Magnus Dehli Vigeland ORCID iD [aut, cre]
Maintainer: Magnus Dehli Vigeland <m.d.vigeland at>
License: GPL-3
NeedsCompilation: no
SystemRequirements: MERLIN ( for multipoint linkage analysis.
Language: en-GB
Materials: README NEWS
CRAN checks: paramlink2 results


Reference manual: paramlink2.pdf


Package source: paramlink2_1.0.4.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): paramlink2_1.0.4.tgz, r-oldrel (arm64): paramlink2_1.0.4.tgz, r-release (x86_64): paramlink2_1.0.4.tgz, r-oldrel (x86_64): paramlink2_1.0.4.tgz
Old sources: paramlink2 archive

Reverse dependencies:

Reverse imports: pedsuite


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